Category: Publication

Connecting During COVID-19: A Protocol of a Volunteer-Based Telehealth Program for Supporting Older Adults’ Health

By Dr Artin Mahdanian

Introduction: Social-distancing due to COVID-19 has led to social isolation, stress, and mental health issues in older adults, while overwhelming healthcare systems worldwide. Telehealth involving phone calls by trained volunteers is understudied and may be a low-cost, scalable, and valuable preventive tool for mental health. In this context, from patient participatory volunteer initiatives, we have adapted…

Religion and Depression: A Review of the Literature

By Dr Artin Mahdanian

Abstract Background: Depressive disorders are among the most important causes of disability and can be considered a major contributor to the global burden of mental illnesses. Religious beliefs and practices have roots in the history of mankind and are broadly prevalent around the world. People with chronic medical and psychiatric conditions employ religion as a…

Can Geriatric Psychiatry Patients Complete Symptoms Self-Reports Using Tablets? A Randomized Study

By Dr Artin Mahdanian

Abstract Background: With our aging population and limited number of geriatric psychiatrists, innovations must be made in order to meet the growing demands for geriatric psychiatry services. Emerging technologies could greatly improve access to care and systematic data collection. Methods: This randomized study compared completion rates and time to completion (primary outcomes) when using iPad technology vs.…

Citalopram and escitalopram: adverse cardiac outcomes in medically ill inpatients

By Dr Artin Mahdanian

Serotonin selective reuptake inhibitors (SSRIs) have widely replaced older tricyclic antidepressants (TCAs) in the treatment of depression and anxiety over the years, given their safer cardiac profile [Glassman, 1998]. Even at therapeutic doses, TCAs commonly cause a slowing of intraventricular conduction through their sodium-channel blocking properties, leading to prolonged PR, QRS and QT intervals [Pacher…

Selective Serotonin Re-Uptake Inhibitors and Hyponatremia in Acutely Medically-Ill Inpatients

By Dr Artin Mahdanian

Abstract Background: Selective Serotonin Reuptake Inhibitors (SSRIs) have become the mainstay of treatment for depression, anxiety, and many other conditions. However, they have been associated with an increased risk of hyponatremia. Little is known about the risk of SSRI-associated hyponatremia in certain potentially at-risk populations, such as patients with acute medical illnesses. Objective: The main objective of…

Are Serotonergic Antidepressants Associated With a Lower Risk of Cerebrovascular Accidents?

By Dr Artin Mahdanian

TO THE EDITOR: Serotonergic antidepressants are one of the most commonly prescribed psychiatric medications. The literature suggests that serotonergic antidepressants may be protective against ischemic cerebrovascular accidents (CVAs),1, 2 which has been thought to be due to effects on platelet activation and aggregation.3 However, the clinical relevance of the association between serotonergic antidepressants and CVAs has been challenged…

Health Canada Warning on Citalopram and Escitalopram–Its Effects on Prescribing in Consultation-Liaison Psychiatry

By Dr Artin Mahdanian

Abstract Background: Reports have suggested that citalopram and escitalopram may prolong the QTc interval, leading Health Canada to issue a warning to limit their dosages in 2012. Little is known about the effects of this warning and similar ones (e.g., by the Food and Drug Administration) on antidepressant prescribing in inpatients with acute medical illness, who…

Serotonergic antidepressants and increased bleeding risk in patients undergoing breast biopsy

By Dr Artin Mahdanian

Abstract Objectives: Recent investigations have shown that serotonergic antidepressant (SAd) use may increase the risk of peri-operative bleeding events. Our objective was to evaluate the possibility of a similar association in patients undergoing radiologic breast biopsies. Methods: We used data from 3890 patients undergoing 6300 biopsy procedures between January 2011 and October 2014 in the Breast Clinic…